A Safety and Activity Study of NS2 in Subjects With Allergic Conjunctivitis
Status:
Completed
Trial end date:
2015-12-01
Target enrollment:
Participant gender:
Summary
This is a randomized, parallel, single center, double masked, vehicle controlled study. The
purpose of this study is to determine the activity and safety of NS2 in patients with grass,
tree or ragweed-pollen induced seasonal allergic conjunctivitis . Subjects will be randomized
1:1 to receive multiple doses of NS2 Ophthalmic Drops (0.5%) or NS2 Ophthalmic Drops Vehicle
(0.0%).
Free aldehydes are thought to be related to inflammatory conditions such as allergic
conjunctivitis. NS2, a small molecule aldehyde trap, is being evaluated to determine whether
it may decrease inflammation by lowering aldehyde levels.