A Research Study of How the Medicine NNC0480-0389 Taken With Semaglutide Works in the Body of Healthy Japanese Men
Status:
Completed
Trial end date:
2021-07-20
Target enrollment:
Participant gender:
Summary
This study looks at how the new medicine called NNC0480-0389 works in the body of Japanese
men when it is given together with semaglutide. Participants will get NNC0480-0389 and
semaglutide or 2 doses of placebo - which treatment participants get is decided by chance.
NNC0480-0389 is a new medicine that has not been previously approved. It means that the
medicine has not yet been approved by the health authorities. Semaglutide is a newly approved
antidiabetic medicine that helps to lower blood sugar levels in patients with type 2
diabetes. NNC0480-0389 is being developed to be given together with semaglutide.NNC0480-0389
targets a different part of the system that regulates sugar levels in the body than
semaglutide. Therefore, it is expected that together NNC0480-0389 and semaglutide will more
effectively lower sugar levels in the blood. Participants will get 2 injections of the study
medicine. It will be injected with a needle into a skin fold on participants' stomach. The
study will last for a maximum of 72 days. Participants will have 10 scheduled visits with the
study doctor. For 1 of the visits participants will stay at the clinic for 6 days (5
nights).The study includes blood sampling.