A Research Study of Greater Occipital Nerve Block as a Treatment for Acute Migraine Attacks
Status:
Unknown status
Trial end date:
2018-06-30
Target enrollment:
Participant gender:
Summary
Several observational studies have shown improvement in episodic migraine with the use of
greater occipital nerve block as an acute therapy, and a recent placebo controlled trial did
not show a decrease in frequency of episodic or chronic migraine; however, there has never
been a placebo controlled trial to investigate the efficacy of GONB as an acute treatment for
headache, and there has been no determination of guidelines for selection of patients who
would be most likely to respond to GONB. In light of the above, the investigators propose a
double-blind, placebo-controlled, randomized trial examining the use of GONB with
lidocaine/bupivocaine in patients with an acute episodic migraine. The results of this trial
are expected to guide more appropriate therapeutic management of these participants and the
optimal use of this procedure. 50 subjects will be entered into this study. This study is
being conducted at Thomas Jefferson University only.