A Research Study Investigating How NNC0385-0434 is Tolerated in People With or Without High Cholesterol Levels
Status:
Completed
Trial end date:
2020-04-23
Target enrollment:
Participant gender:
Summary
In this study, there are two study medicines: NNC0385-0434 (the new medicine being tested)
and placebo (a 'dummy' medicine). Participants will only get one of these medicines - which
one is decided by chance. The study medicine for each person is chosen by a computer. A dummy
medicine (placebo) looks like the study medicine but has no effect on the body. The dummy
medicine needs to be used in the study to find out if the study medicine works as expected.
The dose of the study medicines that participants receive will depend on which group they get
into. The study has 4 groups of 8-15 participants in each. Each group will get a different
dose of NNC0385-0434 or placebo. Participants and the study doctor will not know which of the
study medicine/dose participants will get. However, if a participant's safety is at risk, the
study doctor will be told in order to decide the future treatment. NNC0385-0434 may help to
clear cholesterol from the blood. When there is less cholesterol circulating in the blood
over a long period of time, then there is less risk of arteries (blood vessels) being clogged
or developing diseases of the heart and blood vessels. Each participant will get one
injection under the skin and will be in the study for about 4 months.