A Randomized Trial of Oral Iron Therapy in Fibromyalgia
Status:
Completed
Trial end date:
2015-12-01
Target enrollment:
Participant gender:
Summary
Fibromyalgia (FM) is a disorder with chronic widespread musculoskeletal pain for which no
alternative cause can be identified. The condition is often accompanied by other features
such as fatigue, stiffness, cold intolerance, cognitive impairment, intolerance to external
stimuli, sleep disturbances, anxiety and depression, which significantly affect the quality
of life. Fibromyalgia is characterized by altered pain perception, and studies have shown
fibromyalgia to be more prevalent in patients with iron deficiency anemia. Iron is essential
for a number of enzymes involved in serotonin and dopamine synthesis. Deficiency of
serotonergic neuronal functioning might be related to the pathophysiology of FM.
This study attempts to explore the use of oral iron as a cheap and readily available
alternative for the treatment of FM .
Phase:
Phase 3
Details
Lead Sponsor:
Sanjay Gandhi Postgraduate Institute of Medical Sciences