A Randomized Trial of GVS Alone vs. Propranolol

• Status: Recruiting
• Trial end date: 2025-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Design a randomized trial to compare the effect of endoscopic cyanoacrylate injection obliteration versus non-selective beta-blocker in the primary prevention of gastric variceal bleeding.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Taipei Veterans General Hospital, Taiwan
• Collaborator: National Taiwan University Hospital
• Treatments: Adrenergic beta-Antagonists; Propranolol

Criteria

Inclusion Criteria:

1. patients with live cirrhosis and/or hepatoma

2. Aged 18 to 80, who had endoscopy-Proven EV(-)GV(+)or EVExclusion Criteria:

1. Patients had previous endoscopic, surgical treatment or Transjugular Intrahepatic Portosystemic Shunt

2. Had a terminal illness of any major organ system,such as heart failure, kindey failure,COPD