A Randomized Trial Comparing Oxytocin and Oxytocin + Ergometrine for Prevention of Postpartum Haemorrhage at Caesarean Section

• Status: Completed
• Trial end date: 2014-09-30
• Target enrollment: 0
• Participant gender: Female

Summary

This is a randomized trial comparing oxytocin versus oxytocin + syntometrine in the prevention of post partum haemorrhage in patients undergoing caesarean section

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Pretoria
• Treatments: Ergonovine; Oxytocin; Syntometrine

Criteria

Inclusion Criteria:

• Pregnant women delivering by caesarean section older than 18 years willing and able to give informed consent

Exclusion Criteria:

• • Women not willing or women not able to provide consent

• Women who have a classical caesarean section

• Women younger than 18 years of age

• Women with any of the following conditions will be excluded (ergometrine contra-indicated in patients with these conditions).

• Pre- eclampsia

• Eclampsia,

• Uncontrolled hypertension (hypertension defined as systolic blood pressure more than 140 mm Hg and diastolic blood pressure more than 90 mm Hg)

• Any cardiac lesion

• Impaired liver function

• Impaired kidney function

• Hypersensitivity to any of the active ingredients of the preparations that will be used (Syntometrine® or Syntocinon®)

• Occlusive vascular disease

• Autoimmune vasculitis