Overview

A Randomized, Open-label, Multiple-dose, Crossover Study to Investigate the Pharmacokinetic Drug Interaction Between Rosuvastatin and Telmisartan in Healthy Volunteer

Status:
Completed

Trial end date:
2013-01-01

Target enrollment:

Participant gender:

Summary

This clinical trial is designed to compare the pharmacokinetic characteristics of combination and separate administration of Crestor(Rosuvastatin) and Micardis(Telmisartan). Also investigate drug interaction between separate and combination administration. Total number of subjects is 48. 4 group(12 for 1 group), 2 period, consecutive 6 day administration, 16 days washout after 6th day of administration. The subjects of Part 1 take Crestor alone and Crestor+Micardis combination by a cross-over design during 2 each period. The other subjects of Part 2 take Micardis alone and Crestor+Micardis combination by a cross-over design during 2 each period.

Phase:

Phase 1

Details

Lead Sponsor:

Yuhan Corporation

Treatments:

Rosuvastatin Calcium
Telmisartan