A Randomized-Controlled Trial of Inhaled Hypertonic Saline (7%) to Evaluate the Lung Clearance Index
Status:
Completed
Trial end date:
2014-09-01
Target enrollment:
Participant gender:
Summary
The Lung Clearance Index (LCI) is a non invasive measure of lung function that is more
sensitive than FEV1. It can be used to measure lung function in children younger than 6 years
of age. Therefore, it has a future role in assessing novel therapeutics in the Cystic
Fibrosis (CF) population. As such, determining if it can be used as a short term
pharmacodynamic biomarker is paramount.