A Randomised Trial of a Moisturising Cream in Preventing Recurrence of Hand Eczema

• Status: Completed
• Trial end date: 2008-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to investigate whether a moisturizing cream can prevent hand eczema.Patients with previous hand eczema will be studied. In the second part of the study, it will be explored if a treatment regimen of a topical corticosteroid once daily is not inferior to treatment twice daily.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: ACO Hud Nordic AB
• Collaborator: Smerud Medical Research International AS
• Treatments: Betamethasone; Betamethasone benzoate; Betamethasone sodium phosphate; Betamethasone Valerate; Betamethasone-17,21-dipropionate

Criteria

Inclusion Criteria:

• Clinically proven history of hand eczema

• At inclusion controlled state of hand eczema (≤3 on Hand Eczema Extent Score, HEES)

• Daily use of moisturising treatment

• Either gender

• Age 18 or above

• Written Informed Consent

Exclusion Criteria:

• Possible allergy to ingredients in the study medications

• At study start active psoriatic lesions or active atopic eczema lesions on the hands. Active bacterial, fungal or viral infection of the hands

• Patients who are pregnant or breast-feeding, or who plan to become pregnant during the course of the study

• Use of any concomitant medication that may interfere with the study related activities or assessment of efficacy

• Any patient related factor suggesting potential poor compliance with study procedures (e.g. psychiatric disorders, history of alcohol or substance abuse)

• Any serious medical condition which, in the opinion of the investigator, may interfere with the evaluation of the results

• Inclusion in a study of an investigational drug within 60 days prior to start of treatment