A Prospective Study of The Complement Depletion in Patients With Severe Abdominal Sepsis
Status:
Completed
Trial end date:
2012-03-01
Target enrollment:
Participant gender:
Summary
The role of complement system in bridging innate and adaptive immunity has been confirmed in
various invasive pathogens. The aim of this study is to investigate the alteration of
complement C3 in patients with severe abdominal sepsis and evaluate the role of complement C3
depletion in prognosis of such patients. The relationship between complement C3 depletion and
adaptive immunity is studied meanwhile.