A Prospective Study of Outcome After Therapy for Acromegaly
Status:
Recruiting
Trial end date:
2022-06-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to evaluate hormone values and other markers of disease activity
in a cohort of patients with acromegaly at the time of diagnosis and then prospectively after
surgical or other treatment. This study is designed to determine blood levels of growth
hormone and related hormones and cardiovascular risk markers as well as signs and symptoms of
the disease at diagnosis and how these parameters change over time after surgical or other
therapy. The investigators will also obtain hormonal data in a group of 50 healthy subjects
who will each be studied just once with an oral glucose tolerance test (OGTT). These data
will provide a comparison group to the acromegaly subjects.
Details
Lead Sponsor:
Columbia University
Collaborators:
Icahn School of Medicine at Mount Sinai National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)