A Prospective Study of Different Digoxin Treatment Regimens in Egyptian Hospital
Status:
Completed
Trial end date:
2014-10-01
Target enrollment:
Participant gender:
Summary
Digoxin is the primary cardiac glycoside in clinical use. Because of the narrow therapeutic
index and risk of toxicity, therapeutic drug monitoring is highly recommended. In Egypt, most
cardiologists give digoxin holiday for both atrial fibrillation and heart failure, it is not
clear if the interrupted digoxin regimens are effective since serum digoxin concentrations
might fall below the therapeutic range.
Objective: To evaluate and compare the digoxin serum concentration and patient's quality of
life in the continuous versus interrupted digoxin dosing regimens.