Overview

A Proof of Concept, Phase 2, Double-blind, Randomized Trial With d-Methadone Product Versus Placebo

Status:
Not yet recruiting
Trial end date:
2021-11-30
Target enrollment:
Participant gender:
Summary
Proof of concept, double-blind Randomized Controlled Trial with d-Methadone proposed for the first time for use in the treatment of patients diagnosed with primary, moderate to very severe RLS. Its glutamatergic mechanism of action might be effective on Restless Legs Syndrome arousal pattern and sleep disturbance which highly impair the quality of life of Restless Legs Syndrome's patients. Patients must take study drug once a day for 10 consecutive days.
Phase:
Phase 2
Details
Lead Sponsor:
Mauro Manconi
Collaborator:
Clinical Trial Unit Ente Ospedaliero Cantonale
Treatments:
D-methadone
Methadone