A Preliminary Study of a New Tranexamic Acid Dosing Schedule for Cardiac Surgery
Status:
Completed
Trial end date:
2008-08-01
Target enrollment:
Participant gender:
Summary
Tranexamic acid is administered intravenously to prevent bleeding associated with cardiac
surgery and cardiopulmonary bypass. We have developed an assay for tranexamic acid. We have
developed an alternative dosing schedule for tranexamic acid. The objective of this
preliminary study is to determine if this new dosing schedule can achieve the desired plasma
concentration of tranexamic acid and reduce intra and inter patient variability in tranexamic
acid plasma concentrations relative to the current dosing schedule.