A Placebo-Controlled Study of Clonidine for Fecal Incontinence.
Status:
Completed
Trial end date:
2012-08-01
Target enrollment:
Participant gender:
Summary
Fecal incontinence is the involuntary leakage of stool from the anus. Doctors at Mayo Clinic
are doing a research study to assess the effects of a medication, clonidine, on fecal
incontinence and rectal functions in women. Clonidine has been approved by the Food and Drug
Administration (FDA) for treating high blood pressure, but not for treating incontinence and
rectal functions. The hypothesis of this study is clonidine will improve fecal incontinence,
increase rectal capacity and reduce rectal sensation to a greater extent than placebo in
women.
Phase:
Phase 2
Details
Lead Sponsor:
Mayo Clinic
Collaborators:
National Center for Research Resources (NCRR) National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)