A Pilot Study to Characterize Bile Acid Metabolism and Dysbiosis in Primary Sclerosing Cholangitis
Status:
Completed
Trial end date:
2018-12-01
Target enrollment:
Participant gender:
Summary
The goal of this study is to assess if oral vancomycin can restore the normal bile acid
metabolism of people with Primary Sclerosing Cholangitis and Inflammatory Bowel Disease.
Study participants will provide blood and stool samples in order to evaluate the bile acid
metabolism before a short course of vancomycin and then again after to assess for change. The
investigators will also assess the blood and stool of healthy people, and people with IBD
(without PSC) as a control group.
Phase:
Phase 1
Details
Lead Sponsor:
University of Minnesota University of Minnesota - Clinical and Translational Science Institute