A Pilot Study for the Treatment of Patients With Metastatic and High Risk Sarcomas and Primitive Neuroectodermal Tumors
Status:
Completed
Trial end date:
2000-08-01
Target enrollment:
Participant gender:
Summary
This protocol is designed to test the feasibility of the administration of vincristine,
adriamycin and cytoxan, alternating with the newly developed regimen ifosfamide VP-16 as well
as the efficacy of this therapy in addition to radiotherapy in producing complete responses
and disease-free survival in patients with Ewing's sarcoma, primitive sarcoma of bone,
peripheral neuroepithelioma, and soft tissue sarcoma. This will not be a randomized study but
will be comparable to the large data base of similar patients treated on successive Pediatric
Branch studies.