A Phase III, Randomized, Study of Aspirin and Esomeprazole Chemoprevention in Barrett's Metaplasia
Status:
Unknown status
Trial end date:
2017-05-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming, growing,
or coming back. The use of esomeprazole and aspirin may prevent esophageal cancer in patients
with Barrett's metaplasia. It is not yet known whether esomeprazole is more effective with or
without aspirin in preventing esophageal cancer in patients with Barrett's metaplasia.
PURPOSE: This randomized phase III trial is studying esomeprazole with or without aspirin to
compare how well they work in preventing esophageal cancer in patients with Barrett's
metaplasia.