Overview

A Phase II Trial of Panobinostat and Lenalidomide in Patients With Relapsed or Refractory Hodgkin's Lymphoma

Status:
Completed
Trial end date:
2016-11-16
Target enrollment:
Participant gender:
Summary
This phase II trial studies how well giving panobinostat together with lenalidomide works in treating patients with relapsed or refractory Hodgkin lymphoma. Panobinostat may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Biological therapies, such as lenalidomide, may stimulate the immune system in different ways and stop cancer cells from growing. Giving panobinostat together with lenalidomide may be an effective treatment for Hodgkin lymphoma
Phase:
Phase 2
Details
Lead Sponsor:
Kristie Blum
Ohio State University Comprehensive Cancer Center
Collaborators:
Celgene
Novartis
Treatments:
Histone Deacetylase Inhibitors
Lenalidomide
Panobinostat
Thalidomide