Overview A Phase II Study of Oral LDE225 in Patients With Hedge-Hog (Hh)-Pathway Activated Relapsed Medulloblastoma (MB) Status: Completed Trial end date: 2016-10-05 Target enrollment: Participant gender: Summary This Phase II study evaluated the safety and efficacy of LDE225 in adult and pediatric patients with Hh-pathway activated, relapsed MB. Phase: Phase 2 Details Lead Sponsor: Novartis Pharmaceuticals