Overview

A Phase II Study Of Abraxane and Nexavar in the First-Line Treatment of Locally Advanced or Metastatic Breast Cancer

Status:
Terminated
Trial end date:
2009-05-01
Target enrollment:
Participant gender:
Summary
This is a Phase II, open-label, non-randomized study in patients with locally advanced or metastatic breast cancer. Each cycle will be 4 weeks in length. Patients will receive Abraxane weekly for 3 weeks. Patients will not receive Abraxane during week 4 (rest week). Nexavar will be given continuously. Patients will be radiologically evaluated every 8 weeks for response. Patients will continue to receive study treatment until disease progression or unacceptable toxicity.
Phase:
Phase 2
Details
Lead Sponsor:
Veeda Oncology
Collaborators:
Bayer
Celgene Corporation
Treatments:
Albumin-Bound Paclitaxel
Niacinamide
Paclitaxel
Sorafenib