Overview A Phase I Topotecan Study in Subjects With Cancer and Impaired Renal Function Status: Completed Trial end date: 2012-02-06 Target enrollment: Participant gender: Summary To determine the effect of renal impairment and prior platinum-based chemotherapy on the safety and blood levels of topotecan administered orally Phase: Phase 1 Details Lead Sponsor: GlaxoSmithKlineTreatments: Topotecan