Overview

A Phase I Study of High Dose Simvastatin in Patients With Gastrointestinal Tract Cancer Who Failed to Standard Chemotherapy

Status:
Recruiting

Trial end date:
2020-12-01

Target enrollment:

Participant gender:

Summary

Simvastatin 5-10mg/kg bid for 7 days and 14 days off treatment for 21 days Cohort 1: 7.5 mg/kg bid for 7 days 14 days off Cohort 2: 10 mg/kg bid for 7 days 14 days off Cohort 3: ( ) mg/kg bid for 7 days 14 days off (to be determined based on PK data of cohort 1 and 2) Q 3 weeks

Phase:

Phase 1

Details

Lead Sponsor:

Samsung Medical Center

Treatments:

Simvastatin