Overview

A Phase I Study To Estimate The Effect Of Ketoconazole And Omeprazole On The Pharmacokinetics Of Dimebon In Healthy Subjects Who Are Normal Or Poor CYP2D6 Metabolizers

Status:
Completed

Trial end date:
2009-10-01

Target enrollment:

Participant gender:

Summary

This study will evaluate the potential for a drug-drug interaction of Dimebon with ketoconazole and omeprazole, potent inhibitors of the drug metabolizing enzymes CYP3A4 and CYP2C19, respectively.

Phase:

Phase 1

Details

Lead Sponsor:

Pfizer

Collaborator:

Medivation, Inc.

Treatments:

Ketoconazole
Omeprazole