Overview

A Phase 3 Study of Pelabresib (DAK539) and Ruxolitinib in Myelofibrosis (MF)

Status:
NOT_YET_RECRUITING
Trial end date:
2030-12-27
Target enrollment:
Participant gender:
Summary
The purpose of this trial is to evaluate whether treatment with pelabresib in combination with ruxolitinib leads to improved clinical outcomes compared to ruxolitinib alone in patients with primary myelofibrosis (PMF), post-polycythemia vera myelofibrosis (PPV-MF), or post-essential thrombocythemia myelofibrosis (PET-MF) who have not previously received Janus kinase (JAK) inhibitor therapy.
Phase:
PHASE3
Details
Lead Sponsor:
Novartis Pharmaceuticals
Treatments:
ruxolitinib