A Pharmacokinetic Study of Lithium Before and During Topiramate Dosing in Bipolar Disorder Patients
Status:
Completed
Trial end date:
2002-10-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine the initial (after 1-week of maintenance dosing)
and extended (after 3-weeks of maintenance dosing) effect of topiramate, at doses up to 600
mg/day, on the steady-state pharmacokinetics (absorption, distribution and excretion of the
drug by the body) of lithium carbonate in patients with bipolar disorders.
Phase:
Phase 1
Details
Lead Sponsor:
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.