A Pharmacokinetic Study of Colchicine With an Oral Contraceptive
Status:
Completed
Trial end date:
2008-02-01
Target enrollment:
Participant gender:
Summary
This study will evaluate the effect, if any, of twice daily dosing of colchicine 0.6 mg at
steady state on the steady state pharmacokinetic profile of ethinyl estradiol and
norethindrone (Ortho-Novum 1/35). It will also evaluate the effects, if any, of steady state
ethinyl estradiol and norethindrone on colchicine at steady state. Finally, this study will
assess the safety and tolerability of concurrent use of colchicine and an
estrogen/progesterone-containing oral contraceptive.