A Pharmacokinetic Evaluation of Two Nicotine Patches in Smokers

• Status: Completed
• Trial end date: 2012-03-01
• Target enrollment: 0
• Participant gender: All

Summary

Bioequivalence study to confirm that a NTS with a polyisobutylene (PIB) adhesive from an alternative supplier delivers the same nicotine blood profile as that of the currently approved NTS with a polyisobutylene adhesive from the current supplier.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: GlaxoSmithKline
• Treatments: Nicotine

Criteria

Inclusion Criteria:

• BMI 19-27 kg/m2

• smokes >10 cigarettes per day for preceeding 6 months

Exclusion Criteria:

• inability to stop smoking during study