A Pharmacokinetic Evaluation of Metformin in Relation to the Polymorphism A270S in Healthy Caucasian Volunteers
Status:
Completed
Trial end date:
2010-12-01
Target enrollment:
Participant gender:
Summary
The aim of the study is to evaluate the pharmacokinetics of metformin in healthy Caucasians
volunteers with and without the polymorphism A270S in OCT2,thus the study hypothesis is that
renal clearance of metformin is affected in Caucasian with the known single nucleotide
polymorphisms A270S in OCT2.