Overview

A Open Study of Metronomic Oral Vinorelbine in Combination With Aromatase Inhibitors for the Treatment of Postmenopausal Women With Hormone Receptor Positive,HER2-negative, Advanced Breast Cancer Who Received no Prior Therapy for Advanced Disease

Status:
Terminated

Trial end date:
2020-03-23

Target enrollment:

Participant gender:

Summary

This study is designed to evaluate the clinical effects of the addition of metronomic oral vinorelbine to letrozole and anastrozole. The study will compare the efficacy and tolerability of oral metronomic vinorelbine administered in combination with letrozole or anastrozole, as treatment for hormone receptor-positive advanced or metastatic breast cancer without resistance to Aromatase Inhibitors (AI).

Phase:

Phase 3

Details

Lead Sponsor:

Centre Hospitalier Universitaire de Besancon

Collaborator:

Pierre Fabre Medicament

Treatments:

Anastrozole
Aromatase Inhibitors
Hormones
Letrozole
Vinblastine
Vinorelbine