A New Clinical Use of Ferumoxytol Nanoparticles: An Antibiofilm Treatment
Status:
Completed
Trial end date:
2022-03-10
Target enrollment:
Participant gender:
Summary
The goal of this observational is study is to develop a protocol for root canal biofilms
disinfection using a clinically approved and commercially available iron oxide nanoparticle
formulation Ferumoxytol/H2O2 treatments. This protocol will be testing local single topical
application of Ferumoxytol within the root canal system in patients going through routine
root canal treatment, evaluate its potential as anti-biofilm treatment and compare it to the
clinical gold standard disinfecting solution sodium hypochlorite (positive control) and
saline (negative control).