A New Antibiotic Prophylaxis Regimen to Prevent Bacteremia Following Dental Procedures
Status:
Completed
Trial end date:
2015-05-01
Target enrollment:
Participant gender:
Summary
The aim of this study is to evaluate the efficacy of prophylactic dosage with amoxicillin
(AMX), amoxicillin-clavulanate (AMX-CLV), and a combination of amoxicillin-clavulanate and a
chlorhexidine mouthwash (AMX-CLV-CHX) in the prevention of bacteremia following dental
extractions.
The study hypothesis is that an antimicrobial regimen with amoxicillin-clavulanate will show
higher effectiveness in reducing the prevalence and duration of bacteremia following dental
extractions, than that achieved with the classical amoxicillin regimen.