A Multicentre Randomised Clinical Trial of Laser Treatment Plus Intravitreal Triamcinolone for Diabetic Macular Oedema
Status:
Completed
Trial end date:
2009-05-01
Target enrollment:
Participant gender:
Summary
This study is likely to identify an improved and economical treatment for diabetic macular
oedema, one of the commonest causes of blindness both in Australia and the rest of the
world.The specific aims of the study are to test the following hypotheses:
- That intravitreal triamcinolone followed by laser treatment results in a greater
improvement in visual acuity than placebo followed by laser treatment of eyes with
macular oedema secondary to diabetes;
- That intravitreal triamcinolone followed by laser treatment results in greater degree of
resolution of macular oedema than placebo followed by laser treatment of eyes with
macular oedema secondary to diabetes;
- That intravitreal triamcinolone followed by laser treatment results in a reduced
requirement for further laser treatment to control diabetic macular oedema than placebo
followed by laser treatment;
- That intravitreal triamcinolone followed laser has a manageable and acceptable safety
profile in eyes with diabetic macular edema.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
University of Sydney
Collaborators:
Marsden Eye Centre Marsden Eye Specialists The University of Western Australia University of Melbourne