Overview A Multi-Center Study of Lapatinib in Patients With Trastuzumab-refractory Metastatic Breast Cancer Status: Completed Trial end date: 2020-05-31 Target enrollment: Participant gender: Summary Evaluating the Efficacy of Lapatinib in Combination With Chemotherapy in Patients With Trastuzumab-refractory Metastatic HER2-positive Breast Cancer. Phase: Phase 2 Details Lead Sponsor: Sun Yat-sen UniversityTreatments: CapecitabineLapatinibVinblastineVinorelbine