A Midazolam Drug Interaction Study With PF-04171327

• Status: Completed
• Trial end date: 2009-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to investigate the effects of multiple doses of PF-04171327 on the blood levels (pharmacokinetics) of midazolam

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Pfizer
• Treatments: Midazolam

Criteria

Inclusion Criteria:

• Healthy males and/or females (non-childbearing potential) volunteers.

• Cortisol level within normal reference range of the laboratory.

Exclusion Criteria:

• History of intolerance or significant adverse effect with glucocorticoid (steroid) therapy.

• History or current positive results for HIV, Hepatitis B or C or active TB or currently undergoing treatment for TB.

• Known history of hypersensitivity, allergy severe drug reaction or unable to tolerate midazolam or other benzodiazepines.