Overview

A Mechanistic Test of Treatment Strategies to Foster Practice Quitting

Status:
Not yet recruiting
Trial end date:
2027-08-30
Target enrollment:
0
Participant gender:
All
Summary
Tobacco use disorder is a chronic, relapsing health condition that necessitates a chronic care approach. However, traditional smoking cessation treatment programs allocate nearly all their resources only to those smokers who are willing to set a quit date. This is problematic because few smokers are ready to set a quit date at any given time, and a smoker's stated intention to quit can change rapidly. One novel potential treatment strategy is to foster practice quitting (PQ), defined as attempting to not smoke for a few hours or days, without pressure or expectation to permanently quit. Although a growing body of evidence supports the role of practice quitting in fostering permanent quit attempts and cessation, there is a significant knowledge gap regarding which treatment strategies should be used to engage smokers in practice quitting. The proposed study will test the role of PQ counseling vs. Motivational Interviewing (MI) counseling, and NRT sampling (four-week supply of nicotine lozenges and patches) vs. none.
Phase:
Phase 1/Phase 2
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Rush University Medical Center
Collaborator:
Medical University of South Carolina
Treatments:
Nicotine
Criteria
Inclusion Criteria:

Eligible participants will be males and females who:

1. are 18 years or older

2. report current daily cigarette smoking (≥ 5 cigarettes per day)

3. are not planning to quit in the next 30 days

4. are motivated to quit or engage in a non-cessation goal (i.e., reduce smoking, learn
more about treatment options, and/ or try out skills to change smoking) in the next 6
months

5. are English speaking

6. have access to a smartphone that can be used to complete study procedures

Exclusion Criteria:

Participants will be excluded for any FDA contraindications for NRT use if they:

1. are pregnant/breastfeeding

2. had recent cardiovascular trauma such as myocardial infarction

3. had a stroke within the past 3 months