A Mechanistic Evaluation of the Nociceptive Desensitizing Properties of Topical Capsaicin
Status:
Completed
Trial end date:
2019-12-31
Target enrollment:
Participant gender:
Summary
The aim of this project is to study the role of transient receptor potential (TRP-) channel
V1 (TRPV1+) fibers in the development of cutaneous inflammation induced by epidermal
Ultraviolet-B damage. Moreover, in this project the investigators want to evaluate if the
capsaicin-desensitization action can still be induced in a skin area pretreated with topical,
local anesthetic lidocaine.