A Low-Carbohydrate, Ketogenic Diet Versus Orlistat for Weight Loss

• Status: Completed
• Trial end date: 2007-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This study compares two types of diet interventions: a low carbohydrate ketogenic diet (Atkins) and a low-fat diet combined with a medication (Orlistat).

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: US Department of Veterans Affairs; VA Office of Research and Development
• Treatments: Orlistat

Criteria

Inclusion Criteria:

• Participants must have a VA medical center primary care provider;

• Failed first line diet and exercise recommendations;

• In stable health by screening physical and lab tests;

• Agrees to make regular visits per study protocol;

• Has access to telephone;

• Body mass index (BMI) > or = 27 with obesity-related illness OR BMI > or = 30 with no risk factors;

• No contraindications to Orlistat;

• Not pregnant or breast-feeding;

• No serious mental health illness such as dementia or schizophrenia;

• No use of a weight loss therapy in the month prior to screening.

Exclusion Criteria:

• No VAMC primary care provider

• Unable to attend regular study visits

• No access to telephone

• BMI < 27

• Contraindications to Orlistat

• Pregnancy, breast feeding or planning to become pregnant

• Unstable mental health illness

• Use of a weight loss therapy in the month prior to screening