A Healthy Volunteer And Patient Study To Assess The Safety, Tolerability And Pharmacokinetics Of GSK1265744
Status:
Completed
Trial end date:
2008-11-01
Target enrollment:
Participant gender:
Summary
This study is a Phase I single and repeat dose escalation study of GSK1265744 in healthy
subjects and a single repeat dose cohort in HIV-1 infected subjects. The study is planned to
consist of three parts. Part A will enroll two cohorts with a total of 18 subjects in a
single dose escalation to evaluate safety, tolerability and PK. Part B plans to enroll three
cohorts of 10 subjects to evaluate repeat doses of GSK126744 on safety, tolerability and PK.
Part A and B will enroll healthy volunteers. Part C will enroll HIV-1 patients in a single
cohort of 10 subjects. This cohort will evaluate the effects of repeat dose on safety,
tolerability, PK and efficacy.