This study is carried out to test the safety of a study drug called PRL3-ZUMAB. PRL3-ZUMAB is
an investigational drug that has not yet been approved by the Food and Drug Administration
(FDA) or any other regulatory authorities for commercial purposes. This is the first study in
which PRL3-ZUMAB will be given to humans. The study drug has been tested in animals and was
found to be well-tolerated with minimal side effects. This research study will test different
doses of the drug to see which dose is safest in people.