A Feasibility Study of Smoking Cessation Program in Radiation Oncology

• Status: Completed
• Trial end date: 2007-04-01
• Target enrollment: 0
• Participant gender: All

Summary

To test the feasibility of an intensive behavioral and pharmacologic tobacco cessation program for radiation oncology patients and their families/companions.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Indiana University School of Medicine
• Collaborator: Walther Cancer Institute
• Treatments: Bupropion

Criteria

Inclusion Criteria:

• Eligibility for Radiotherapy Patients

• age 18 years or older

• receiving three weeks or more of external beam radiotherapy

• report smoking one or more cigarettes in the past 30 days or self-identify as a smoker

• Cancer Stage:

• Stage I-III

• IVa Head and Neck Malignancy is allowed

• Stage I-IV breast, prostate, testis or lymphoma also allowed

• at least one year life expectancy

• have given written informed consent

• KPS 70-100

Eligibility for Family/Companions of Radiotherapy Patients (Note: Family members/companions are eligible for this protocol regardless of whether the index radiotherapy patient is eligible or willing to participate.)

• age 18 years or older

• at least one year life expectancy

• radiotherapy patient is receiving three weeks or more of external beam radiotherapy

• Person is committed to bringing/accompanying the patient to radiotherapy at least three days per week.

• report smoking one or more cigarettes in the past 30 days or self-identify as a smoker

• Family member/companion of patients under radiotherapy treatment for any stage of cancer

• have given written informed consent

• KPS 70-100

Exclusion Criteria:

• Exclusion Criteria for both Radiotherapy Patients and their Families/Companions

• serious or unstable cardiac, renal, hypertensive, pulmonary, endocrine, or neurologic disorders, as assessed by the study-site physician

• a current diagnosis of major depressive episode or a history of panic disorder, psychosis, bipolar disorder, or eating disorders

• pregnancy or lactation

• any history of allergy/intolerance or adverse reaction to bupropion

• history of seizure disorder, bulimia or anorexia nervosa

• use of an MAOi within 14 days

• current use of another antidepressant

• abrupt discontinuation of alcohol or sedatives

• unwilling/unable to meet with the behavioral interventionalist for 20 minutes, at least 3 days per week during the course of radiotherapy