A Drug to Drug Interaction Study of Sotagliflozin With Hydrochlorothiazide
Status:
Completed
Trial end date:
2018-03-02
Target enrollment:
Participant gender:
Summary
Primary Objective:
To assess the effects of multiple-dose hydrochlorothiazide (HCTZ) on the steady-state
pharmacokinetics (PK) of sotagliflozin.
Secondary Objectives:
- To assess the safety and tolerability of multiple-dose sotagliflozin with and without
co-administration of multiple-dose HCTZ
- To assess the effects of multiple-dose sotagliflozin on the steady-state PK of HCTZ
- To assess the effects of multiple-dose HCTZ on the steady-state PK of
sotagliflozin-3-O-glucuronide