Overview

A Drug-drug Interaction Trial in Healthy Female Participants to Investigate the Effect of Aprocitentan on Combined Hormonal Contraceptives

Status:
COMPLETED

Trial end date:
2025-02-21

Target enrollment:

Participant gender:

Summary

The goal of this clinical trial is to learn if drug aprocitentan has an effect on hormonal contraceptives in healthy female volunteers. The main question it aims to answer is: Does aprocitentan modify the fate of hormonal contraceptives in the body? Trial participants will: * Take a single dose of hormonal contraceptives (fixed combination) alone * Take aprocitentan every day for 2 weeks * Take a single dose of the same hormonal contraceptives at the same time as the 10th administration of aprocitentan.

Phase:

PHASE1

Details

Lead Sponsor:

Idorsia Pharmaceuticals Ltd.

Treatments:

aprocitentan
Ethinyl Estradiol-Norgestrel Combination