Overview

A Drug-Drug Interaction Study of CYP3A4 Inhibition and Pan-CYP Induction on APX001

Status:
Completed
Trial end date:
2020-03-03
Target enrollment:
Participant gender:
Summary
This is a Phase 1, open-label study to evaluate the drug-drug interaction potential of a strong CYP3A4 inhibitor (itraconazole) and a pan-CYP inducer (rifampin) on APX001 in two parallel groups of healthy subjects.
Phase:
Phase 1
Details
Lead Sponsor:
Amplyx Pharmaceuticals
Pfizer
Treatments:
Hydroxyitraconazole
Itraconazole
Rifampin