A Dose Escalation Study of Carfilzomib Taken With Thalidomide and Dexamethasone in Relapsed AL Amyloidosis
Status:
Completed
Trial end date:
2019-10-21
Target enrollment:
Participant gender:
Summary
This study evaluates the safety and efficacy of carfilzomib used in combination with
thalidomide and dexamethasone in patients with relapsed AL amyloidosis. The trial begins with
a dose escalation phase, in which the maximum tolerated and recommended dose will be
determined. The trial will then open into an expansion phase in which the combination
efficacy is assessed.