A Dose Escalation Study Using Collagenase Clostridium Histolyticum in the Treatment of Lipoma
Status:
Completed
Trial end date:
2013-10-01
Target enrollment:
Participant gender:
Summary
The purpose of this research is to evaluate the safest and most effective dose of a Food and
Drug Administration (FDA) approved drug (XIAFLEX) in the treatment of lipoma (fatty tumors of
varying sizes that occur commonly in the adult population). The fat in the lipoma is like
normal fat except that it is enclosed in a balloon-like structure which is made of collagen
(fibrous tissue). Treatment of the lipoma with an injection of XIAFLEX (a protein that breaks
down collagen fibers) may dissolve the collagen/fibrous strands thereby decreasing the size
of the lipoma or removing it.