A Cross Over Pilot Study of Abobotulinum Toxin A (Dysport) as a Treatment for Task-dependent Upper Limb Tremor
Status:
Recruiting
Trial end date:
2022-12-01
Target enrollment:
Participant gender:
Summary
Task-dependent upper limb tremor is a disorder that frequently impairs patients' function and
quality of life. Few studies exist that quantify the improvements in motor performance and
disability with botulinum toxin (injections). The study team aims to perform an exploratory
pilot trial using toxin Type A (Dysport) in 25 patients with task-dependent upper limb
tremor, to refine quantitative measures of performance using blinded video analysis,
demonstrate efficacy and tolerability of injections, and provide power calculations for a
potential future multi-centered double blinded clinical trial.
Phase:
Phase 4
Details
Lead Sponsor:
David M. Simpson
Collaborator:
Ipsen
Treatments:
abobotulinumtoxinA Botulinum Toxins, Type A onabotulinumtoxinA