A Comparison of the Perioperative Hemodynamic Effects of Remifentanil and Esmolol in Intracranial Surgery
Status:
Completed
Trial end date:
2014-09-01
Target enrollment:
Participant gender:
Summary
It was hypothesized that the use of esmolol as an alternative to remifentanil with
sevoflurane inhalation anesthesia during intracranial surgery, could provide better
hemodynamic conditions and cause lesser side effects in the perioperative period. It was the
main objective of this study to compare the effect of esmolol and remifentanil on the
incidence of tachycardia and hypertension and the intraoperative fentanyl consumption. The
comparison of postoperative troponine I and creatine phosphokinase levels and EKG changes
were the secondary objectives.