A Comparison of the Effects of Intraoperative Administration of Metoprolol or Esmolol on General Anesthetic Requirement
Status:
Completed
Trial end date:
2015-09-02
Target enrollment:
Participant gender:
Summary
We will compare three study groups receiving metoprolol, esmolol, or placebo. Level of
anesthesia will be titrated to achieve the same range of BIS value in all groups. Our
hypothesis is that the metoprolol and esmolol groups will require a lower level of anesthetic
agent to achieve the targeted BIS range, compared to the placebo group.
Our objective is to clarify if metoprolol, in a dose range used for perioperative cardiac
protection, decreases anesthetic requirement.
Phase:
N/A
Details
Lead Sponsor:
University of Oklahoma
Treatments:
Anesthetics Anesthetics, General Esmolol Metoprolol